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Post-transcriptional modifications could be new target in fight against Alzheimer’s disease

A recent study, published in the journal PLOS Biology, has revealed that a reduction in mRNA methylation can alleviate the […]

SNO proteins identified as drivers of Alzheimer’s disease in women

Researchers have unlocked new insights into the molecular mechanism of Alzheimer’s disease (AD), which may explain why women are at […]

Exploring Alzheimer’s disease using single-cell/nucleus RNA sequencing data

Scientists have developed a network-based methodology that leverages single-cell/nucleus RNA sequencing data to uncover novel therapeutic targets for Alzheimer’s disease. […]

Researchers identify candidate variants related to Alzheimer’s disease

In a recent study, researchers identified 11 rare genetic variants related to Alzheimer’s disease through high-risk pedigree studies. Alzheimer’s disease […]

Spatial transcriptomics can unravel cellular interactions in Alzheimer’s disease

This article was compiled from a recent webinar, delivered by Professor Bart de Strooper, who is the Director of UK […]

Novel mechanisms that cause tau protein clumping in brain diseases

A team of researchers at the Case Western Reserve University School of Medicine has taken a major step towards understanding […]

The Genetics Of Alzheimer’s: Uncovering new Mechanisms and Drug Targets

An understanding of the environmental and genetic risk of Alzheimer’s Disease is vital for the production of more effective therapies. […]

Alzheimer’s research: LRP6-Val variant is linked to synapse loss and cognitive decline

A new study, published in Science, suggests that deficient Wnt signalling may contribute to synapse loss and cognitive decline in […]

Reproducibility: The science communities’ ticking timebomb. Can we still trust published research?

Is science in the throes of a “reproducibility crisis”? If someone followed the same methods, techniques, and reagents as your […]

The strengths of single-cell and spatial omics in drug discovery

Please note the transcript has been edited for brevity and clarity. FLG: Hello, everyone, and welcome to our interview with […]